Titan A.E. (2000)
Titan A.E. suffered when its original director and producer were fired $30 million into the production budget. It never fully recovered, even after the directors of Anastasia tried to salvage things. The film was such a catastrophe that it forced FOX Animation Studios to close its doors. Rupert Murdoch himself blamed the atrocious box office sales for the 14% loss at News Corp. Titan A.E. racked up $100 million in estimated losses.