A Star is Born
Though she'd been featured in other projects, Gaga's defining breakout role in Hollywood was surely A Star is Born alongside Bradley Cooper. Cooper approached Gaga after she'd performed at a fundraiser and asked if she'd work on the project with him. Gaga walked away from the film with a National Board of Review and Critics' Choice Award, and nominations for the Academy Award, Golden Globe Award, Screen Actor's Guild Award, and BAFTA Award for Best Actress.