John Candy, 43 Years Old
"The Great Outdoors" and "Uncle Buck" wouldn't be what they were without comedic legend John Candy. His most notable performance was in the John Hughes classic, "Planes, Trains, and Automobiles." His death was ruled as a heart attack, though an autopsy was never performed. He had various unfinished projects, including a film adaptation of John Kennedy Toole's novel "A Confederacy of Dunces."