Shelby Eatenton-Latchcherie, Steel Magnolias
This movie is polarizing for those who don't ethically align with the reason Shelby died. However, for those who do subscribe to her method of thinking, Shelby's death was absolutely soul-crushing. Even after getting a donated kidney from her mother, Shelby's type 1 diabetes kills her and prevents her from taking care of the child that she so desperately wanted.