Brittany Murphy, Big Smile
Britney Murphey was an unfortunate casualty to the turn of the 2000s into the 2010s. After starring in numerous successful movies like Clueless, Riding in Cars With Boys, and 8 Mile, Murphy's career took a nosedive around 2008. In 2009, Murphey passed away due to pneumonia and anemia while being mistreated by doctors and having taken a near-lethal dose of inaccurately prescribed pharmaceuticals.