Jodie Foster in The Silence of the Lambs
Anthony Hopkins' legendary performance as prolific serial killer Dr. Hannibal Lecter scared the socks off more than just the audience. Although Hopkins met with Jodie Foster prior to filming for a table read, she was so terrified of him afterward that she refused to say another word to him off-camera for the duration of production. Foster went out of her way to dodge Hopkins: "We got to the end of the movie and really never had a conversation," she said. "I avoided him as best as I could."