Ellen Pompeo
In SoHo circa the 1990s, Ellen Pompeo was working behind the scenes as a bartender. A casting agent loved her charisma and tried to offer her acting advice, which she misinterpreted as flirting. Once it was all cleared up though, she took the advice and landed roles in Friends and Law & Order: SVU, leading to her best-known role to date, Meredith Grey on Grey's Anatomy.